The Crucial Role of Set and Setting in Psychedelic-Based Therapy

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In recent years, there has been a resurgence of interest in psychedelic-based therapies, including ketamine-assisted therapy, as potential tools for addressing various mental health issues, including depression, anxiety, and post-traumatic stress disorder. One of the cornerstones of successful and safe psychedelic experiences is the concept of "set and setting." This dynamic duo plays a pivotal role in shaping the outcome of these therapies and ensuring a transformative and healing journey.

Defining Set and Setting

 In ketamine-assisted psychotherapy as well as other psychedelic therapies, set and setting are crucial to providing the most therapeutic experience for the client. Set refers to the mindset, intentions, and emotional state of the individual undergoing the psychedelic experience. It encompasses their psychological and emotional readiness for the journey. Setting, on the other hand, refers to the physical, social, and emotional environment in which the psychedelic experience takes place. This includes factors such as the location, lighting, comfort, and the presence of trained therapists or guides. 

The Synergy Between Set and Setting

The interplay between set and setting can be likened to a delicate dance between the internal landscape of the mind and the external environment. The effects of psychedelics are known to be highly sensitive to the individual's state of mind and surroundings. Let's delve into why each of these components is crucial:

Set: Shaping the Inner Experience

  • Mindset and Intention: A positive and open mindset can contribute to a more profound and insightful experience. Setting clear intentions before the journey can guide the experience toward therapeutic insights and self-discovery.

  • Emotional State: Individuals with unresolved traumas or deeply ingrained negative emotions should approach psychedelic therapy with caution. An unstable emotional state might lead to overwhelming experiences. Proper preparation and support are vital.

  • Readiness and Awareness: Being prepared for the potential challenges and intensity of a psychedelic journey can enhance the ability to navigate difficult emotions or experiences that arise during the session.

Flourish Mindset Approach to Set 

Flourish Mindset, takes a holistic and trauma-informed approach to our ketamine therapy services. Our therapists use a thorough and effective process to understand your personal goals for ketamine therapy, your history, and your background. This allows us to curate a personalized treatment experience that meets you where you are in your psychological journey. Using an intake session, preparation sessions, and integration sessions following ketamine therapy sessions, we support you in creating a mindset that promotes growth, healing, and flourishing. 

Setting: Crafting the External Environment

Comfort and Safety: The physical environment should be comfortable, safe, and conducive to relaxation. This helps minimize potential anxiety or distress during the experience.

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  • Aesthetic and Atmosphere: The aesthetics of the surroundings, including lighting, colors, and sounds, can influence the emotional tone of the journey. Creating a calming and aesthetically pleasing atmosphere can contribute to a positive experience.

  • Presence of Guides or Therapists: Trained therapists or guides can provide a sense of security and support throughout the journey. Their presence can help individuals navigate challenging emotions and guide them toward insights and healing.

Flourish Mindset Setting

Our beautiful Los Angeles office creates a peaceful setting that is warm and welcoming, open and clear to provide you with the space to explore yourself in comfort. We provide a comfortable space to relax and release so you receive the maximum benefits from your ketamine therapy. Ketamine-assisted psychotherapy in our Los Angeles office differs from ketamine infusion clinics, which typically administer your ketamine treatment in a sterile medical room, with harsh lighting, and limited support. Given the importance of setting for one’s psychedelic experience, we feel it is important to provide an aesthetically pleasing environment, with soft lighting, a curated playlist, artwork, and live plants to support your journey. 

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The Ripple Effect: Set, Setting, and Integration

The impact of set and setting goes beyond the immediate psychedelic experience. It often ripples into the post-session phase known as integration. This phase involves reflecting on the insights gained, processing emotions, and incorporating newfound perspectives into daily life.

An empowering set and nurturing setting set the stage for a more productive integration process. The insights gained from the journey can be integrated into everyday life more effectively when the external and internal environments have supported the experience.

The Takeaway: Holistic Preparation for Transformation


Psychedelic-based therapy holds tremendous potential for personal growth and healing. However, its success is intimately tied to the thoughtful cultivation of both the individual's inner landscape (set) and the external environment (setting). Neglecting either aspect can lead to unexpected or undesired outcomes.

As the field of psychedelic therapy advances, practitioners and participants alike are recognizing the value of fostering a harmonious synergy between set and setting. By doing so, we honor the depth and complexity of the psychedelic experience and open doors to profound healing and transformation. Remember, the voyage within is as much about the inner terrain as it is about the landscape around us.

Choose a ketamine assisted psychotherapy provider that takes care and attention to your individual needs, to create a set and setting that allows you to thrive and integrate your ketamine therapy into your daily life for lasting changes.

Ketamine Assisted Psychotherapy in Los Angeles

Our Ketamine Assisted Psychotherapy in Los Angeles provides a peaceful and individualized experience taking great care in establishing a set and setting that will promote your Ketamine Therapy experience of recovery and growth. Learn more about our Ketamine Assisted Therapy services in Los Angeles or Book a Free consultation to meet with a trained Ketamine Assisted Psychotherapist. You can start your therapy journey by following these simple steps:

Other Services Offered with Flourish Mindset

KETAMINE THERAPY isn’t the only service offered at Flourish Mindset. Our team is happy to offer a variety of services in support of your mental health. These include in-person therapy options in Los Angeles and ONLINE THERAPY options across California. Other services offered include COUPLES THERAPY, EMDR THERAPY, and CHILD AND TEEN THERAPY. We also offer ANXIETY THERAPY, DEPRESSION THERAPY, and THERAPY FOR SEXUAL TRAUMA.

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